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MOLECULAR GENETICS

THE MAJOR STEPS IN GENETIC ENGINEERING

1869 DNA isolated
1944  DNA proved to be the hereditary material.
1953 DNA structure determined
1961 DNA can be split on heating and stuck back together again on cooling. DNA hybridisation possible.
1962 The first restriction endonucleases discovered. Molecular scissors.
1966 The genetic code worked out

1967

DNA ligase discovered. Molecular glue. Fragments of DNA can be stuck together.
1973 DNA cloning carried out.
1977 Rapid sequencing of DNA developed.
1982 Transgenic mice and fruit flies produced.
1985 Genetic fingerprinting developed.
1989 Cystic fibrosis gene cloned and sequenced.
1990 Trials for gene therapy begin

1994

Genetically manipulated organisms for food.
2000 The human genome worked out.

 

 

 

 

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© Paul Billiet 2009